This thesis addresses challenging aspects of drug design that require explicit consideration of more than a single drug-target interaction in an unchanging environment. In the first half, the common challenge of designing ...

A tandem benzannulation-ring closing metathesis strategy for the efficient synthesis of benzo-fused nitrogen heterocycles such as dihydroquinolines, benzazepines, and benzazocines has been developed. This strategy is based ...

The microscopic chemical mechanisms of heterogeneous reactions involving HC on crystalline ice and nitric acid trihydrate (NAT) are of fundamental interest to physical chemists, because such reactions yield "active" chlorine ...

Solar thermal fuels and fluorescent solar concentrators provide two ways in which the energy from the sun can be harnessed and stored. While much progress has been made in recent years, there is still much more to learn ...

This thesis focuses on development of polymeric materials that can alter their functions according to temperature changes. We chose poly(N-isopropylacrylamide) (polyNIPA) as a platform, which phase-separates from water ...

Conjugated polymers have found various uses in optoelectronic applications, including chemical sensors, light-emitting diodes, and photovoltaic materials. In this thesis, we investigate the effect of having a molecular ...