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Next-generation transgenic mice for optogenetic analysis of neural circuits

dc.contributor.authorAsrican, Brent
dc.contributor.authorAugustine, George J.
dc.contributor.authorBerglund, Ken
dc.contributor.authorChen, Susu
dc.contributor.authorChow, Nick
dc.contributor.authorDeisseroth, Karl
dc.contributor.authorFeng, Guoping
dc.contributor.authorGloss, Bernd
dc.contributor.authorHira, Riichiro
dc.contributor.authorHoffmann, Carolin
dc.contributor.authorKasai, Haruo
dc.contributor.authorKatarya, Malvika
dc.contributor.authorKim, Jinsook
dc.contributor.authorKudolo, John
dc.contributor.authorLee, Li Ming
dc.contributor.authorLo, Shun Qiang
dc.contributor.authorMancuso, James
dc.contributor.authorMatsuzaki, Masanori
dc.contributor.authorNakajima, Ryuichi
dc.contributor.authorQiu, Li
dc.contributor.authorTan, Gregory
dc.contributor.authorTang, Yanxia
dc.contributor.authorTsuda, Sachiko
dc.contributor.authorWen, Lei
dc.contributor.authorZhang, Xuying
dc.contributor.authorZhao, Shengli
dc.contributor.authorTing, Jonathan Thomas
dc.date.accessioned2014-03-17T18:19:13Z
dc.date.available2014-03-17T18:19:13Z
dc.date.issued2013-11
dc.date.submitted2013-05
dc.identifier.issn1662-5110
dc.identifier.urihttp://hdl.handle.net/1721.1/85681
dc.description.abstractHere we characterize several new lines of transgenic mice useful for optogenetic analysis of brain circuit function. These mice express optogenetic probes, such as enhanced halorhodopsin or several different versions of channelrhodopsins, behind various neuron-specific promoters. These mice permit photoinhibition or photostimulation both in vitro and in vivo. Our results also reveal the important influence of fluorescent tags on optogenetic probe expression and function in transgenic mice.en_US
dc.language.isoen_US
dc.publisherFrontiers Research Foundationen_US
dc.relation.isversionofhttp://dx.doi.org/10.3389/fncir.2013.00160en_US
dc.rightsArticle is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.en_US
dc.sourceFrontiersen_US
dc.titleNext-generation transgenic mice for optogenetic analysis of neural circuitsen_US
dc.typeArticleen_US
dc.identifier.citationAsrican, Brent, George J. Augustine, Ken Berglund, Susu Chen, Nick Chow, Karl Deisseroth, Guoping Feng, et al. “Next-Generation Transgenic Mice for Optogenetic Analysis of Neural Circuits.” Front. Neural Circuits 7 (2013).en_US
dc.contributor.departmentMassachusetts Institute of Technology. Department of Brain and Cognitive Sciencesen_US
dc.contributor.departmentMcGovern Institute for Brain Research at MITen_US
dc.contributor.mitauthorFeng, Guopingen_US
dc.contributor.mitauthorTing, Jonathan Thomasen_US
dc.relation.journalFrontiers in Neural Circuitsen_US
dc.eprint.versionFinal published versionen_US
dc.type.urihttp://purl.org/eprint/type/JournalArticleen_US
eprint.statushttp://purl.org/eprint/status/PeerRevieweden_US
dspace.orderedauthorsAsrican, Brent; Augustine, George J.; Berglund, Ken; Chen, Susu; Chow, Nick; Deisseroth, Karl; Feng, Guoping; Gloss, Bernd; Hira, Riichiro; Hoffmann, Carolin; Kasai, Haruo; Katarya, Malvika; Kim, Jinsook; Kudolo, John; Lee, Li Ming; Lo, Shun Qiang; Mancuso, James; Matsuzaki, Masanori; Nakajima, Ryuichi; Qiu, Li; Tan, Gregory; Tang, Yanxia; Ting, Jonathan T.; Tsuda, Sachiko; Wen, Lei; Zhang, Xuying; Zhao, Shenglien_US
dc.identifier.orcidhttps://orcid.org/0000-0002-8021-277X
mit.licensePUBLISHER_POLICYen_US
mit.metadata.statusComplete


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