Browsing by Author "Xavier, R. J."
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Development of a Colon Cancer GEMM-Derived Orthotopic Transplant Model for Drug Discovery and Validation
Martin, Eric S.; Belmont, P. J.; Sinnamon, M. J.; Richard, L. G.; Yuan, J.; e.a. (American Association for Cancer Research, 2013-02)Purpose: Effective therapies for KRAS-mutant colorectal cancer (CRC) are a critical unmet clinical need. Previously, we described genetically engineered mouse models (GEMM) for sporadic Kras-mutant and non-mutant CRC ...