Continuous flow photocatalysis enhanced using an aluminum mirror: rapid and selective synthesis of 2′-deoxy and 2′,3′-dideoxynucleosides
Name
Shen Bedore Sniady Jamison CC-COM-05-2012-033356 revised.pdf
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711.77 KB
Format
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Author(s)
Shen, Bo
Bedore, Matthew W.
Sniady, Adam
Jamison, Timothy F.
Date Issued
June 2012
Journal
Chemical Communications
Publisher
Royal Society of Chemistry
Citation
Shen, Bo, Matthew W. Bedore, Adam Sniady, and Timothy F. Jamison. “Continuous flow photocatalysis enhanced using an aluminum mirror: rapid and selective synthesis of 2′-deoxy and 2′,3′-dideoxynucleosides.” Chemical Communications 48, no. 60 (2012): 7444.
Version
Author's final manuscript
Abstract
A unique photochemical flow reactor featuring quartz tubing, an aluminum mirror and temperature control has been developed for the photo-induced electron-transfer deoxygenation reaction to produce 2′-deoxy and 2′,3′-dideoxynucleosides. The continuous flow format significantly increased the efficiency and selectivity of the reaction.
MIT Department
Massachusetts Institute of Technology. Department of Chemistry
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Creative Commons Attribution-Noncommercial-Share Alike 3.0
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DOI of Published Version
https://doi.org/10.1039/c2cc33356b
