NF-κB Fans the Flames of Lung Carcinogenesis
Name
Jacks_NF-KB fans.pdf
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59.26 KB
Format
Adobe PDF
Checksum (MD5)
76a607996885d126296420afad6313c9
Author(s)
Wong, Kwok-Kin
Dranoff, Glenn
Jacks, Tyler E
Date Issued
March 2010
Journal
Cancer Prevention Research
Publisher
American Association for Cancer Research
Citation
Wong, K. K., T. Jacks, and G. Dranoff. “NF- B Fans the Flames of Lung Carcinogenesis.” Cancer Prevention Research 3, no. 4 (April 4, 2010): 403-405.
Version
Author's final manuscript
Abstract
This perspective on Deng et al. (beginning on p. 424 in this issue of the journal) examines the link between NF-κB and lung tumorigenesis. Experiments in genetically engineered mouse models of lung cancers are elucidating protumorigenic roles of NF-κB activation in lung cancer pathogenesis. Our growing understanding of the tumor-promoting NF-κB downstream effector pathways could lead to the development of novel approaches for lung cancer therapy and chemoprevention.
MIT Department
Koch Institute for Integrative Cancer Research at MIT
Terms of Use
Creative Commons Attribution-Noncommercial-Share Alike 3.0
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1158/1940-6207.capr-10-0042
