Directed Heterodimerization: Stereocontrolled Assembly via Solvent-Caged Unsymmetrical Diazene Fragmentation
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Movassaghi_Directed heterodimerization.pdf
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2.73 MB
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Author(s)
Movassaghi, Mohammad
Ahmad, Omar K.
Lathrop, Stephen
Date Issued
July 2011
Journal
Journal of the American Chemical Society
Publisher
American Chemical Society (ACS)
Citation
Movassaghi, Mohammad, Omar K. Ahmad, and Stephen P. Lathrop. “Directed Heterodimerization: Stereocontrolled Assembly via Solvent-Caged Unsymmetrical Diazene Fragmentation.” Journal of the American Chemical Society 133, no. 33 (August 24, 2011): 13002-13005.
Version
Author's final manuscript
Abstract
A general strategy for the directed and stereocontrolled assembly of carbon–carbon linked heterodimeric hexahydropyrroloindoles is described. The stepwise union of complex amines in the form of mixed diazenes followed by photoexpulsion of dinitrogen in a solvent cage provides completely guided assembly at challenging C[3 over sp]–C[3 over sp] and C[3 over sp]–C[2 over sp] connections.
MIT Department
Massachusetts Institute of Technology. Department of Chemistry
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Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
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DOI of Published Version
https://doi.org/10.1021/ja2057852
