Exploration of large scale manufacturing of polydimethylsiloxane (PDMS) microfluidic devices
Name
78263832-MIT.pdf
Description
Full printable version
Size
2.45 MB
Format
Adobe PDF
Checksum (MD5)
b008f9973632a13eb80d21dc6b7a468a
Author(s)
Hum, Philip W. (Philip Wing-Jung)
Advisor(s)
David E. Hardt.
Date Issued
2006
Publisher
Massachusetts Institute of Technology
Abstract
Discussion of the current manufacturing process of polydimethylsiloxane (PDMS) parts and the emergence of PDMS use in biomedical microfluidic devices addresses the need to develop large scale manufacturing processes for the fabrication of said devices. Casting PDMS parts is found to be the best mass production process after evaluating several different production methods. Automation of the manufacturing process is introduced as a solution to the need for mass production. Changing variables within the production process and its effects are also discussed with the recommendation being made for using low viscosity pre-cured PDMS, high temperature curing and high vacuum degassing techniques to produce high quality parts at high production rates. The further development of producing two-sided PDMS parts is recommended by investigating the usage of a non-closed aspect limited casting process.
Description
Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2006.
Includes bibliographical references (leaves 54-56).
Subjects
Mechanical Engineering.
MIT Department
Massachusetts Institute of Technology. Department of Mechanical Engineering
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