Single-Cell Profiling of Ebola Virus Disease In Vivo Reveals Viral and Host Dynamics
Name
1-s2.0-S0092867420313088-main.pdf
Description
Published version
Size
36.8 MB
Format
Adobe PDF
Checksum (MD5)
64c9aff5810790329d309e646ef6b4cb
Author(s)
Kotliar, Dylan
Lin, Aaron E
Logue, James
Hughes, Travis K
Khoury, Nadine M
Raju, Siddharth S
Wadsworth, Marc H
Chen, Han
Kurtz, Jonathan R
Dighero-Kemp, Bonnie
Date Issued
2020
Journal
Cell
Publisher
Elsevier BV
Citation
Kotliar, Dylan, Lin, Aaron E, Logue, James, Hughes, Travis K, Khoury, Nadine M et al. 2020. "Single-Cell Profiling of Ebola Virus Disease In Vivo Reveals Viral and Host Dynamics." Cell, 183 (5).
Version
Final published version
Abstract
© 2020 The Author(s) Single-cell profiling of circulating immune cells during Ebola virus (EBOV) infection in non-human primates resolves molecular correlates of viral tropism, characterizes replication dynamics within infected cells, and distinguishes expression changes that are mediated by viral infection from those due to cytokine signaling.
MIT Department
Harvard University--MIT Division of Health Sciences and Technology
Massachusetts Institute of Technology. Department of Chemistry
Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Koch Institute for Integrative Cancer Research at MIT
Ragon Institute of MGH, MIT and Harvard
Terms of Use
Creative Commons Attribution 4.0 International license
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1016/J.CELL.2020.10.002
