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Automated affinity selection for rapid discovery of peptide binders

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sword-2022-03-15T18:51:37.original.xml (130 B)
Original SWORD entry document
Author(s)
Zhang, Genwei
•
Li, Chengxi
•
Quartararo, Anthony J
•
Loas, Andrei
•
Pentelute, Bradley L
Date Issued
2021
Journal
Chemical Science
Publisher
Royal Society of Chemistry (RSC)
Citation
Zhang, Genwei, Li, Chengxi, Quartararo, Anthony J, Loas, Andrei and Pentelute, Bradley L. 2021. "Automated affinity selection for rapid discovery of peptide binders." Chemical Science, 12 (32).
Version
Final published version
Abstract
This work reports an automated affinity selection-mass spectrometry (AS-MS) approach amenable to both de novo peptide binder discovery and affinity maturation of known binders in a high-throughput and selective manner.
MIT Department
Massachusetts Institute of Technology. Department of Chemistry
Koch Institute for Integrative Cancer Research at MIT
Massachusetts Institute of Technology. Center for Environmental Health Sciences
Terms of Use
Creative Commons Attribution 3.0 unported license
https://creativecommons.org/licenses/by/3.0/
Persistent DSpace Link
https://hdl.handle.net/1721.1/141202
DOI of Published Version
https://doi.org/10.1039/D1SC02587B
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