Expanding the landscape of antibody discovery
Name
1-s2.0-S2667237524003266-main.pdf
Description
Published version
Size
1.69 MB
Format
Adobe PDF
Checksum (MD5)
dabd3b36b6c32cd0c1f33dc855be7bb0
Author(s)
Johnson, Shelbe
DeKosky, Brandon J
Date Issued
December 2024
Journal
Cell Reports Methods
Publisher
Elsevier BV
Citation
Johnson, Shelbe and DeKosky, Brandon J. 2024. "Expanding the landscape of antibody discovery." Cell Reports Methods, 4 (12).
Version
Final published version
Abstract
Library:library screening technologies hold substantial promise for paired antibody:antigen discovery, but challenges have persisted. In this issue of Cell Reports Methods, Wagner et al. introduce a method that combines antibody-ribosome-mRNA complexes, antigen cell surface display, and single-cell RNA sequencing to successfully screen diverse antibody gene libraries against a library of viral receptor proteins.
MIT Department
Massachusetts Institute of Technology. Department of Chemical Engineering
Ragon Institute of MGH, MIT and Harvard
Koch Institute for Integrative Cancer Research at MIT
Terms of Use
Creative Commons Attribution-NonCommercial-NoDerivatives
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1016/j.crmeth.2024.100936
