Palladium(0)-Catalyzed Intermolecular Amination of Unactivated C[3 over sp]-H Bonds
Name
Buchwald_Palladium (0)-catalyzed.pdf
Size
1.28 MB
Format
Adobe PDF
Checksum (MD5)
a945cbc154627bc9fafabb5e428f7f7f
Author(s)
Pan, Jun
Su, Mingjuan
Buchwald, Stephen Leffler
Date Issued
August 2011
Journal
Angewandte Chemie International Edition
Publisher
Wiley Blackwell
Citation
Pan, Jun, Mingjuan Su, and Stephen L. Buchwald. “Palladium(0)-Catalyzed Intermolecular Amination of Unactivated C[3 over sp]-H Bonds.” Angewandte Chemie International Edition 50, no. 37 (September 5, 2011): 8647-8651.
Version
Author's final manuscript
Abstract
Filling out the space: The title reaction of unactivated C[3 over sp]-H bonds using aryl amines as the nitrogen source is disclosed (see scheme; dba=dibenzylideneacetone, Tf=trifluoromethanesulfonyl). Either the C-N cross-coupling product or the C-H amination product could be accessed selectively by adjusting the steric environment of the substrate.
MIT Department
Massachusetts Institute of Technology. Department of Chemistry
Terms of Use
Creative Commons Attribution-Noncommercial-Share Alike 3.0
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1002/anie.201102880
