Electrophysiological Source Imaging: A Noninvasive Window to Brain Dynamics
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ARBE_ESI_Submitted.pdf
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3.86 MB
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Author(s)
He, Bin
Sohrabpour, Abbas
Brown, Emery Neal
Liu, Zhongming
Date Issued
June 2018
Journal
Annual Review of Biomedical Engineering
Publisher
Annual Reviews
Citation
He, Bin et al. "Electrophysiological Source Imaging: A Noninvasive Window to Brain Dynamics." Annual Review of Biomedical Engineering 20 (June 2018): 171-196. © 2018 Annual Reviews
Version
Author's final manuscript
Abstract
Brain activity and connectivity are distributed in the three-dimensional space and evolve in time. It is important to image brain dynamics with high spatial and temporal resolution. Electroencephalography (EEG) and magnetoencephalography (MEG) are noninvasive measurements associated with complex neural activations and interactions that encode brain functions. Electrophysiological source imaging estimates the underlying brain electrical sources from EEG and MEG measurements. It offers increasingly improved spatial resolution and intrinsically high temporal resolution for imaging large-scale brain activity and connectivity on a wide range of timescales. Integration of electrophysiological source imaging and functional magnetic resonance imaging could further enhance spatiotemporal resolution and specificity to an extent that is not attainable with either technique alone. We review methodological developments in electrophysiological source imaging over the past three decades and envision its future advancement into a powerful functional neuroimaging technology for basic and clinical neuroscience applications. Keywords: electrophysiological source imaging; EEG; MEG; source localization; functional connectivity; inverse problem
MIT Department
Harvard University--MIT Division of Health Sciences and Technology
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Creative Commons Attribution-Noncommercial-Share Alike
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DOI of Published Version
https://doi.org/10.1146/annurev-bioeng-062117-120853
