Capacity-Speed Relationships in Prefrontal Cortex
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Prabhakaran-2011-Capacity-Speed Relat.pdf
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855.89 KB
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Author(s)
Prabhakaran, Vivek
Rypma, Bart
Narayanan, Nandakumar S.
Meier, Timothy B.
Austin, Benjamin P.
Nair, Veena A.
Naing, Lin
Thomas, Lisa E.
Gabrieli, John D. E.
Date Issued
November 2011
Journal
PLoS ONE
Publisher
Public Library of Science
Citation
Prabhakaran, Vivek et al. “Capacity-Speed Relationships in Prefrontal Cortex.” Ed. André Aleman. PLoS ONE 6.11 (2011): e27504. Web. 23 Feb. 2012.
Version
Final published version
Abstract
Working memory (WM) capacity and WM processing speed are simple cognitive measures that underlie human performance in complex processes such as reasoning and language comprehension. These cognitive measures have shown to be interrelated in behavioral studies, yet the neural mechanism behind this interdependence has not been elucidated. We have carried out two functional MRI studies to separately identify brain regions involved in capacity and speed. Experiment 1, using a block-design WM verbal task, identified increased WM capacity with increased activity in right prefrontal regions, and Experiment 2, using a single-trial WM verbal task, identified increased WM processing speed with increased activity in similar regions. Our results suggest that right prefrontal areas may be a common region interlinking these two cognitive measures. Moreover, an overlap analysis with regions associated with binding or chunking suggest that this strategic memory consolidation process may be the mechanism interlinking WM capacity and WM speed.
MIT Department
Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
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Creative Commons Attribution
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DOI of Published Version
https://doi.org/10.1371/journal.pone.0027504
