A microfabricated dielectrophoretic micro-organism concentrator
Name
56978461-MIT.pdf
Description
Full printable version
Size
13.94 MB
Format
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Checksum (MD5)
f1a9281eef816cb0038b34db36ad7fad
Author(s)
Muller, Rikky, 1980-
Advisor(s)
Joel Voldman.
Date Issued
2004
Publisher
Massachusetts Institute of Technology
Abstract
This project focuses on the development of a micro-organism concentrator. Pathogen detection, particularly MEMS based detection, is often limited by sample concentration. The proposed concentrator will interface with a pathogen detector. This type of pathogen concentrator can be useful for many kinds of applications including water purification systems, medical applications and biological warfare agent detection. Due to the nature of these applications, the concentrator must be able to operate under real-world conditions, and be robust to particulates and variations in solution conductivity. The concentrator is an active filter, which concentrate bacteria in solution using negative dielectrophoresis, which pushes objects away from the electrodes toward field minima. An electric field barrier is set up to guide cells toward a concentrated outlet flow path while the bulk of the fluid, which permeates the electric field barrier, is sent to a waste outlet. The cells are collected at the outlet and selectively released by turning off the applied voltage. I have fully designed and modeled the characteristics of the proposed concentrator and successfully fabricated the design. I have characterized the system throughput using polystyrene beads and I have characterized the system electrically using lumped circuit element models.
Description
Thesis (M. Eng. and S.B.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, June 2004.
"May 2004."
Includes bibliographical references (leaves 83-85).
Subjects
Electrical Engineering and Computer Science.
MIT Department
Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
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