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Smartphone and Wearable Device-Based Digital Phenotyping to Understand Substance use and its Syndemics

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Author(s)
Lee, Jasper S.
•
Browning, Emma
•
Hokayem, Joanne
•
Albrechta, Hannah
•
Goodman, Georgia R.
•
Venkatasubramanian, Krishna
•
Dumas, Arlen
•
Carreiro, Stephanie P.
•
O’Cleirigh, Conall
•
Chai, Peter R.
Date Issued
March 4, 2024
Journal
Journal of Medical Toxicology
Publisher
Springer US
Citation
Lee, J.S., Browning, E., Hokayem, J. et al. Smartphone and Wearable Device-Based Digital Phenotyping to Understand Substance use and its Syndemics. J. Med. Toxicol. 20, 205–214 (2024).
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Author's final manuscript
Abstract
Digital phenotyping is a process that allows researchers to leverage smartphone and wearable data to explore how technology use relates to behavioral health outcomes. In this Research Concepts article, we provide background on prior research that has employed digital phenotyping; the fundamentals of how digital phenotyping works, using examples from participant data; the application of digital phenotyping in the context of substance use and its syndemics; and the ethical, legal and social implications of digital phenotyping. We discuss applications for digital phenotyping in medical toxicology, as well as potential uses for digital phenotyping in future research. We also highlight the importance of obtaining ground truth annotation in order to identify and establish digital phenotypes of key behaviors of interest. Finally, there are many potential roles for medical toxicologists to leverage digital phenotyping both in research and in the future as a clinical tool to better understand the contextual features associated with drug poisoning and overdose. This article demonstrates how medical toxicologists and researchers can progress through phases of a research trajectory using digital phenotyping to better understand behavior and its association with smartphone usage.
MIT Department
Koch Institute for Integrative Cancer Research at MIT
Terms of Use
Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
Persistent DSpace Link
https://hdl.handle.net/1721.1/159807
DOI of Published Version
https://doi.org/10.1007/s13181-024-01000-5
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