Studies on the total synthesis of gymnocin B
Name
1008887385-MIT.pdf
Description
Full printable version
Size
8.15 MB
Format
Adobe PDF
Checksum (MD5)
f87ed4f8e9259931e21bfe2a0f26bb78
Author(s)
Sittihan, Satapanawat
Advisor(s)
Timothy F. Jamison.
Date Issued
2017
Publisher
Massachusetts Institute of Technology
Abstract
Progress toward the biomimetic total synthesis of gymnocin B is described. Synthesis of the ABCDEFGH fragment has been completed in 30 steps longest linear sequence, using three different types of epoxide-opening cascades and one fragment coupling. Synthesis of the KLMNO fragment has been completed in 27 steps longest linear sequence, using one epoxide-opening cascade and one fragment coupling. The completion plan of gymnocin B is also detailed. [chemical formulas]
Description
Thesis: Ph. D. in Organic Chemistry, Massachusetts Institute of Technology, Department of Chemistry, 2017.
Cataloged from PDF version of thesis.
Includes bibliographical references.
Subjects
Chemistry.
MIT Department
Massachusetts Institute of Technology. Department of Chemistry
Terms of Use
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