Separation of Microscale Chiral Objects by Shear Flow
Name
Marcos-2009-Separation of Micros.pdf
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846.74 KB
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Author(s)
Powers, Thomas R.
Fu, Henry C.
Stocker, Roman
Marcos
Date Issued
April 2009
Journal
Physical Review Letters
Publisher
American Physical Society
Citation
Marcos et al. “Separation of Microscale Chiral Objects by Shear Flow.” Physical Review Letters 102.15 (2009): 158103.© 2009 The American Physical Society.
Version
Final published version
Abstract
We show that plane parabolic flow in a microfluidic channel causes nonmotile, helically shaped bacteria to drift perpendicular to the shear plane. Net drift results from the preferential alignment of helices with streamlines, with a direction that depends on the chirality of the helix and the sign of the shear rate. The drift is in good agreement with a model based on resistive force theory, and separation is efficient (>80%) and fast (<2 s). We estimate the effect of Brownian rotational diffusion on chiral separation and show how this method can be extended to separate chiral molecules.
MIT Department
Massachusetts Institute of Technology. Department of Civil and Environmental Engineering
Massachusetts Institute of Technology. Department of Mechanical Engineering
Terms of Use
Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
Persistent DSpace Link
DOI of Published Version
http://dx.doi.org/10.1103/PhysRevLett.102.158103
