Multiplex Particle Focusing via Hydrodynamic Force in Viscoelastic Fluids
Name
Lee-2013-Multiplex particle f.pdf
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1.49 MB
Format
Adobe PDF
Checksum (MD5)
530135d5f6ac4bd7b575ba7180eca230
Author(s)
Lee, Doo Jin
Brenner, Howard
Youn, Jae Ryoun
Song, Young Seok
Date Issued
November 2013
Journal
Scientific Reports
Publisher
Nature Publishing Group
Citation
Lee, Doo Jin, Howard Brenner, Jae Ryoun Youn, and Young Seok Song. “Multiplex Particle Focusing via Hydrodynamic Force in Viscoelastic Fluids.” Scientific Reports 3 (November 19, 2013).
Version
Final published version
Abstract
We introduce a multiplex particle focusing phenomenon that arises from the hydrodynamic interaction between the viscoelastic force and the Dean drag force in a microfluidic device. In a confined microchannel, the first normal stress difference of viscoelastic fluids results in a lateral migration of suspended particles. Such a viscoelastic force was harnessed to focus different sized particles in the middle of a microchannel, and spiral channel geometry was also considered in order to take advantage of the counteracting force, Dean drag force that induces particle migration in the outward direction. For theoretical understanding, we performed a numerical analysis of viscoelastic fluids in the spiral microfluidic channel. From these results, a concept of the ‘Dean-coupled Elasto-inertial Focusing band (DEF)’ was proposed. This study provides in-depth physical insight into the multiplex focusing of particles that can open a new venue for microfluidic particle dynamics for a concrete high throughput platform at microscale.
MIT Department
Massachusetts Institute of Technology. Department of Chemical Engineering
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DOI of Published Version
https://doi.org/10.1038/srep03258
