20.441 / 2.79J / 3.96J / HST.522J Biomaterials-Tissue Interactions (BE.441), Fall 2003
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20-441-fall-2003/contents/index.htm
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Checksum (MD5)
721068d4e47738aa2ca7dede803194fe
Author(s)
Yannas, Ioannis
Spector, Myron
Alternative Title
Biomaterials-Tissue Interactions (BE.441)
Date Issued
December 2003
Abstract
This course is an introduction to principles of materials science and cell biology underlying the design of medical implants, artificial organs, and matrices for tissue engineering. Topics include methods for biomaterials surface characterization and analysis of protein adsorption on biomaterials. Molecular and cellular interactions with biomaterials are analyzed in terms of unit cell processes, such as matrix synthesis, degradation, and contraction. It also covers mechanisms underlying wound healing and tissue remodeling following implantation in various organs. Other areas include tissue and organ regeneration; design of implants and prostheses based on control of biomaterials-tissue interactions; comparative analysis of intact, biodegradable, and bioreplaceable implants by reference to case studies. Also addressed are criteria for restoration of physiological function for tissues and organs.
Subjects
medical implants
artificial organs
tissue engineering
matrix
biomaterials
protein adsorption
unit cell process
wound healing
tissue remodeling
tissue regeneration
organ regeneration
prosthesis
biodegradable
bioreplaceable implants
BE.441
2.79J
3.96J
HST.522J
2.79
3.96
HST.522
MIT Department
Massachusetts Institute of Technology. Department of Biological Engineering
Massachusetts Institute of Technology. Department of Civil and Environmental Engineering
Harvard University--MIT Division of Health Sciences and Technology
Massachusetts Institute of Technology. Department of Materials Science and Engineering
Massachusetts Institute of Technology. Department of Mechanical Engineering
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