Creating Isolated Liquid Compartments Using Photopatterned Obstacles in Microfluidics
Name
PhysRevApplied.7.044013.pdf
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2.67 MB
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Adobe PDF
Checksum (MD5)
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Author(s)
Lee, Hyundo
Gupta, Ankur
Hatton, Trevor Alan
Doyle, Patrick S
Date Issued
April 2017
Journal
Physical Review Applied
Publisher
American Physical Society
Citation
Lee, Hyundo; Gupta, Ankur; Hatton, T. Alan and Doyle, Patrick S. "Creating Isolated Liquid Compartments Using Photopatterned Obstacles in Microfluidics." Physical Review Applied 7, no. 044013 (April 2017): 1-13 © 2017 American Physical Society
Version
Final published version
Abstract
We propose a method to trap liquid (both oil and water) in a microchannel by sequentially injecting oil and water (or vice versa) over photopatterned obstacles with controlled wetting properties. We present a simple geometrical model to understand the liquid-entrapment process and predict the evolution of the water/oil interface over an obstacle. Our analysis provides an analytic solution that can successfully predict useful properties such as angular position of pinch-off and the amount of captured liquid. We show that we are able to obtain a liquid bridge over two circular obstacles, and we are also able to predict the condition for the formation of a bridge. We further demonstrate the effect of the obstacle shape and how a sudden change in gradient results in larger liquid entrapment. We also demonstrate the ability to entrap isolated liquid chambers for parallel experimentation.
MIT Department
Massachusetts Institute of Technology. Department of Chemical Engineering
Massachusetts Institute of Technology. Department of Mechanical Engineering
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Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
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DOI of Published Version
https://doi.org/10.1103/PhysRevApplied.7.044013
