Spatially resolved light propagation in tissue-like media
Name
54039223-MIT.pdf
Description
Full printable version
Size
7.36 MB
Format
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Checksum (MD5)
917327cd31915048e85e14edf516c252
Author(s)
Zeskind, Julie E. (Julie Erin), 1981-
Advisor(s)
Michael S. Feld.
Date Issued
2002
Publisher
Massachusetts Institute of Technology
Abstract
The work presented in this thesis is part of a larger project designed to monitor and diagnose Alzheimer's disease non-invasively in vivo using spatially resolved nearinfrared (NIR) spectroscopy. Alzheimer's disease is one of the most common forms of senile dementia occurring in the elderly population, and at present has no cure. The first step in developing a monitoring instrument involves differentiating the optical properties of tissue. In this body of work, a protocol and algorithm for deriving the scattering and absorption coefficients for a spatially resolved reflectance apparatus was developed, characterized, and tested. In models with tissue-like properties, this protocol and algorithm works to derive the appropriate scattering and absorption information, which is the first step in developing a spatially resolved NIR detection device.
Description
Thesis (M.Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2002.
Includes bibliographical references.
Subjects
Electrical Engineering and Computer Science.
MIT Department
Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
Terms of Use
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