Small and Large Ribosomal Subunit Deficiencies Lead to Distinct Gene Expression Signatures that Reflect Cellular Growth Rate
Name
nihms-1515260.pdf
Description
Accepted version
Size
1.29 MB
Format
Adobe PDF
Checksum (MD5)
e17a2c5f6acd054f76ffbc293f786a63
Author(s)
Mertins, Philipp
Regev, Aviv
Date Issued
January 2019
Journal
Molecular Cell
Publisher
Elsevier BV
Citation
Cheng, Ze et al. “Small and Large Ribosomal Subunit Deficiencies Lead to Distinct Gene Expression Signatures that Reflect Cellular Growth Rate.” Molecular Cell 73 (2019): 36-47 © 2019 The Author(s)
Version
Author's final manuscript
Abstract
In this issue of Molecular Cell, Cheng et al. report specific and dose-dependent gene expression changes resulting from decreased ribosome levels, including distinct gene expression signatures resulting from loss of genes encoding members of either the large or small ribosomal subunit.
Subjects
Cell Biology
Molecular Biology
MIT Department
Massachusetts Institute of Technology. Department of Biology
Koch Institute for Integrative Cancer Research at MIT
Terms of Use
Creative Commons Attribution-NonCommercial-NoDerivs License
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1016/j.molcel.2018.10.032
