7.340 Under the Radar Screen: How Bugs Trick Our Immune Defenses, Spring 2007
Author(s)
Grotenbreg, Gijsbert
Paquet, Marie-Eve
Alternative Title
Under the Radar Screen: How Bugs Trick Our Immune Defenses
Date Issued
June 2007
Abstract
In this course, we will explore the specific ways by which microbes defeat our immune system and the molecular mechanisms that are under attack (phagocytosis, the ubiquitin/proteasome pathway, MHC I/II antigen presentation). Through our discussion and dissection of the primary research literature, we will explore aspects of host-pathogen interactions. We will particularly emphasize the experimental techniques used in the field and how to read and understand research data. Technological advances in the fight against microbes will also be discussed, with specific examples. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.
Subjects
HIV
mycobacterium tuberculosis
malaria
influenza
immune system
pathogens
viruses
bacteria
parasites
microbes
phagocytosis
ubiquitin/proteasome pathway
MHC I/II antigen presentation
phagocytosis
Salmonella
pathogen-associated molecular patterns
PAMP
Toll-like receptors
TLR
Vaccinia virus
Proteasome
Ubiquitin; deubiquinating enzymes
DUB
Herpes simplex virus
HSV
Yersinia
viral budding
Human cytomegalovirus
HCMV
Histocompatiblity
AIDS
Kaposi Sarcoma-Associated Herpes virus
Mixoma virus
Epstein Barr virus
EBV
Burkitt?s B cell lymphoma
MIT Department
Massachusetts Institute of Technology. Department of Biology
Terms of Use
This site (c) Massachusetts Institute of Technology 2023. Content within individual courses is (c) by the individual authors unless otherwise noted. The Massachusetts Institute of Technology is providing this Work (as defined below) under the terms of this Creative Commons public license ("CCPL" or "license") unless otherwise noted. The Work is protected by copyright and/or other applicable law. Any use of the work other than as authorized under this license is prohibited. By exercising any of the rights to the Work provided here, You (as defined below) accept and agree to be bound by the terms of this license. The Licensor, the Massachusetts Institute of Technology, grants You the rights contained here in consideration of Your acceptance of such terms and conditions.
Persistent DSpace Link
