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  4. Copper-Catalyzed Oxytrifluoromethylation of Unactivated Alkenes

Copper-Catalyzed Oxytrifluoromethylation of Unactivated Alkenes

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Author(s)
Zhu, Rong
•
Buchwald, Stephen Leffler
Date Issued
July 2012
Journal
Journal of the American Chemical Society
Publisher
American Chemical Society (ACS)
Citation
Zhu, Rong, and Stephen L. Buchwald. “Copper-Catalyzed Oxytrifluoromethylation of Unactivated Alkenes.” Journal of the American Chemical Society 134, no. 30 (August 2012): 12462–12465.
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Author's final manuscript
Abstract
A mild, versatile, and convenient method for the efficient oxytrifluoromethylation of unactivated alkenes based on a copper-catalyzed oxidative difunctionalization strategy has been developed. This methodology provides access to a variety of classes of synthetically useful CF[subscript 3]-containing building blocks from simple starting materials.
MIT Department
Massachusetts Institute of Technology. Department of Chemistry
Terms of Use
Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
Persistent DSpace Link
http://hdl.handle.net/1721.1/94323
DOI of Published Version
https://doi.org/10.1021/ja305840g
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