Copper-Catalyzed Oxytrifluoromethylation of Unactivated Alkenes
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Buchwald_Copper-catalyzed.pdf
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Author(s) •
Zhu, Rong
Buchwald, Stephen Leffler
Date Issued
July 2012
Journal
Journal of the American Chemical Society
Publisher
American Chemical Society (ACS)
Citation
Zhu, Rong, and Stephen L. Buchwald. “Copper-Catalyzed Oxytrifluoromethylation of Unactivated Alkenes.” Journal of the American Chemical Society 134, no. 30 (August 2012): 12462–12465.
Version
Author's final manuscript
Abstract
A mild, versatile, and convenient method for the efficient oxytrifluoromethylation of unactivated alkenes based on a copper-catalyzed oxidative difunctionalization strategy has been developed. This methodology provides access to a variety of classes of synthetically useful CF[subscript 3]-containing building blocks from simple starting materials.
MIT Department
Massachusetts Institute of Technology. Department of Chemistry
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Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
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DOI of Published Version
https://doi.org/10.1021/ja305840g