A combined microfluidic/dielectrophoretic microorganism concentrator
Name
78616940-MIT.pdf
Description
Full printable version
Size
10.69 MB
Format
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Checksum (MD5)
3fadcb37a46936fe46c33db5f8e1eceb
Author(s)
Gadish, Nitzan
Advisor(s)
Joel Voldman.
Date Issued
2005
Publisher
Massachusetts Institute of Technology
Abstract
This thesis presents the development of a high-throughput microfluidic microorganism concentrator for pathogen detection applications. Interdigitated electrodes lining the bottom of the channel use positive dielectrophoretic forces to trap particles. A passive mixer is used to circulate the liquid in the channel, transporting particles to within the trapping region of the electrodes. Samples are extracted and their concentrations measured using a spectrophotometer. Concentration enhancements up to 40x at 500 gl/min flowrate using polystyrene microspheres and up to 10x at 100 gll/min flowrate using B. subtilis spores are achieved.
Description
Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2005.
Includes bibliographical references (p. 71-72).
Subjects
Electrical Engineering and Computer Science.
MIT Department
Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
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