Interactome analysis brings splicing into focus
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13059_2015_Article_707.pdf
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425.05 KB
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Checksum (MD5)
6b12c7a65c290d2609bdab0963961a16
Author(s)
Dominguez, Daniel
Burge, Christopher B
Date Issued
July 2015
Journal
Genome Biology
Publisher
BioMed Central
Citation
Dominguez, Daniel, and Christopher B. Burge. "Interactome analysis brings splicing into focus." Genome Biology. 2015 Jul 07;16(1):135.
Version
Final published version
Abstract
The spliceosome is a huge molecular machine that assembles dynamically onto its pre-mRNA substrates. A new study based on interactome analysis provides clues about how splicing-regulatory proteins modulate assembly of the spliceosome to either activate or repress splicing.
MIT Department
Massachusetts Institute of Technology. Department of Biological Engineering
Massachusetts Institute of Technology. Department of Biology
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Creative Commons Attribution
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1186/s13059-015-0707-0
