Tectorial Membrane Traveling Waves Underlie Sharp Auditory Tuning in Humans
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Tectorial membrane traveling.pdf
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Author(s)
Nakajima, Hideko H.
Farrahi, Shirin
Ghaffari, Roozbeh
Sellon, Jonathan Blake
Freeman, Dennis M.
Date Issued
August 2016
Journal
Biophysical Journal
Publisher
Elsevier
Citation
Farrahi, Shirin et al. “Tectorial Membrane Traveling Waves Underlie Sharp Auditory Tuning in Humans.” Biophysical Journal 111, 5 (September 2016): 921–924 © 2016 Biophysical Society
Version
Final published version
Abstract
Our ability to understand speech requires neural tuning with high frequency resolution, but the peripheral mechanisms underlying sharp tuning in humans remain unclear. Sharp tuning in genetically modified mice has been attributed to decreases in spread of excitation of tectorial membrane traveling waves. Here we show that the spread of excitation of tectorial membrane waves is similar in humans and mice, although the mechanical excitation spans fewer frequencies in humans—suggesting a possible mechanism for sharper tuning.
MIT Department
Harvard University--MIT Division of Health Sciences and Technology
Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
Massachusetts Institute of Technology. Research Laboratory of Electronics
Terms of Use
Creative Commons Attribution-NonCommercial-NoDerivs License
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DOI of Published Version
https://doi.org/10.1016/j.bpj.2016.07.038
