Interfacing devices with cells
Name
Voldman-2009-Interfacing devices with cells.pdf
Size
1.54 MB
Format
Adobe PDF
Checksum (MD5)
d53501ef001ef47143c033e7e7649f34
Author(s)
Voldman, Joel
Date Issued
June 2009
Journal
67th Device Research Conference Digest
Publisher
Institute of Electrical and Electronics Engineers (IEEE)
Citation
Voldman, Joel. “Interfacing Devices with Cells.” IEEE, 2009. 243–244. © Copyright 2009 IEEE
Version
Final published version
Abstract
To detect electrical properties of cells, we have developed a method called iso-dielectric separation (IDS), where cells are placed in a spatially varying electric field and a spatially varying conductivity gradient that forces them to the location in a channel where their net polarizability (p) is zero. At that location, the force on the cell, given by the dielectrophoretic force (F = p·Nabla E) will go to zero. Cells with different polarizabilities will end up in different locations in the channel, thus separating cells based upon electrical properties. The physical implementation of the method is described in Figure 3, and consists of a glass chip with patterned electrodes to create the field, along with microfluidics to deliver cells and create the conductivity gradient.
MIT Department
Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
Terms of Use
Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1109/DRC.2009.5354848
