Renal artery anatomy assessed by quantitative analysis of selective renal angiography in 1,000 patients with hypertension
Name
nihms-1030768.pdf
Description
Accepted version
Size
832.16 KB
Format
Adobe PDF
Checksum (MD5)
d7fe915733aecdda38cb756545c1dcdc
Author(s)
Tzafriri, A Rami
Edelman, Elazer R
Mahfoud, Felix
Date Issued
May 2018
Journal
EuroIntervention
Publisher
Europa Digital & Publishing
Citation
Lauder, Lucas et al. “Renal artery anatomy assessed by quantitative analysis of selective renal angiography in 1,000 patients with hypertension.” EuroIntervention, vol. 14, no. 1, 2018, pp. 121-128 © 2018 The Author(s)
Version
Author's final manuscript
Abstract
Aims: With increasing attention to renovascular causes and targets for hypertension there arises a critical need for more detailed knowledge of renal arterial anatomy. However, a standardised nomenclature is lacking. The present study sought to develop a standardised nomenclature for renal anatomy considering the complexity and variation of the renal arterial tree and to assess the applicability of the nomenclature. Methods and results: One thousand hypertensive patients underwent invasive selective renal artery angiography in nine centres. Further, renovasography was performed in 249 healthy swine as a surrogate for normotensive anatomy. Anatomical parameters were assessed by quantitative vascular analysis. Patients' mean blood pressure was 168/90±26/17 mmHg. The right main renal artery was longer than the left (41±15 mm vs. 35±13 mm, p<0.001), but the left had a greater diameter (5.4±1.2 vs. 5.2±1.2 mm, p<0.001). Accessory renal arteries and renal artery disease were documented in 22% and 9% of the patients, respectively. Other than exhibiting a longer left main renal artery in uncontrolled hypertensives (+2.7 mm, p=0.034) there was no anatomical difference between patients with controlled and uncontrolled hypertension. Main renal artery mean diameter was smaller in patients with impaired kidney function (GFR <90 ml/min, left -0.5 mm, right -0.4 mm, both p<0.001). Conclusions: Renal arterial anatomy differs between sides but shows no difference between patients with and without blood pressure control. Impaired GFR was associated with small main renal artery diameter.
MIT Department
Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Terms of Use
Creative Commons Attribution-Noncommercial-Share Alike
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.4244/EIJ-D-18-00112
