Ratiometric and intensity-based zinc sensors built on rhodol and rhodamine platforms
Name
Tomat and Lippard Inorg Chem.pdf
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2.52 MB
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Checksum (MD5)
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Author(s)
Tomat, Elisa
Lippard, Stephen J.
Date Issued
September 2010
Journal
Inorganic Chemistry
Publisher
American Chemical Society
Citation
Tomat, Elisa, and Stephen J. Lippard. “Ratiometric and Intensity-Based Zinc Sensors Built on Rhodol and Rhodamine Platforms.” Inorganic Chemistry 49 (2010): 9113-9115. Web. 15 Dec. 2011. © 2011 American Chemical Society
Version
Author's final manuscript
Abstract
A xanthene-forming condensation reaction yields rhodol and rhodamine dyes carrying a zinc-binding ligand that includes the aniline-type nitrogen donor of the fluorophores. Upon zinc coordination in neutral aqueous solution, rhodol RF3 behaves as a ratiometric sensor, and rhodamine RA1 acts as a turn-off intensity-based indicator. Both fluorescent compounds bind the divalent zinc cation with micromolar affinity.
Description
Synthetic procedures and product characterization data, zinc binding analysis methods, selectivity and pH dependence charts. This material is available free of charge via the Internet at http://pubs.acs.edu.
MIT Department
Massachusetts Institute of Technology. Department of Chemistry
Terms of Use
Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
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DOI of Published Version
https://doi.org/10.1021/ic101513a
