The Angelman Approach : hacking DNA to treat a rare disease
Name
1015183006-MIT.pdf
Description
Full printable version
Size
1.22 MB
Format
Adobe PDF
Checksum (MD5)
62ebaa6f74dc09995892b915c3f9bfe2
Author(s)
Levy, Brandon A
Advisor(s)
Marcia Bartusiak.
Alternative Title
Hacking DNA to treat a rare disease
Hacking deoxyribonucleic acid to treat a rare disease
Date Issued
2017
Publisher
Massachusetts Institute of Technology
Abstract
One of every hundred children is born with a disease caused by a single abnormal gene. In the case of Angelman Syndrome, the genetic defect leaves patients mentally disabled, largely or completely unable to speak, and prone to seizures and sleep difficulties. Many Angelman researchers are trying to figure out precisely how those symptoms develop, but why study all the individual effects when you could go right to the root of the problem? Recent advances in medicine and technology are increasingly allowing clinicians to treat genetic illnesses by directly manipulating patients' DNA, and a number of scientists are now investigating ways to leverage those discoveries for individuals with Angelman Syndrome. Their work could lead to potent therapies for the disease, and - maybe - even a cure.
Description
Thesis: S.M. in Science Writing, Massachusetts Institute of Technology, Department of Comparative Media Studies/Writing, 2017.
Cataloged from PDF version of thesis.
Includes bibliographical references (pages 18-20).
Subjects
Comparative Media Studies.
Graduate Program in Science Writing.
MIT Department
Massachusetts Institute of Technology. Graduate Program in Science Writing
Terms of Use
MIT theses are protected by copyright. They may be viewed, downloaded, or printed from this source but further reproduction or distribution in any format is prohibited without written permission.
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