Vibrio chromosomes share common history
Name
1471-2180-10-137.pdf
Size
969.62 KB
Format
Adobe PDF
Checksum (MD5)
00a5ad401a22e5d3ba07eb98deb2ce5d
Author(s)
Kirkup, Benjamin
Chang, LeeAnn
Chang, Sarah
Gevers, Dirk
Polz, Martin F.
Date Issued
May 2010
Journal
BMC Microbiology
Publisher
BioMed Central Ltd
Citation
Kirkup, Benjamin C et al. “Vibrio chromosomes share common history.” BMC Microbiology. 2010 May 10;10(1):137.
Version
Final published version
Abstract
Abstract Background While most gamma proteobacteria have a single circular chromosome, Vibrionales have two circular chromosomes. Horizontal gene transfer is common among Vibrios, and in light of this genetic mobility, it is an open question to what extent the two chromosomes themselves share a common history since their formation. Results Single copy genes from each chromosome (142 genes from chromosome I and 42 genes from chromosome II) were identified from 19 sequenced Vibrionales genomes and their phylogenetic comparison suggests consistent phylogenies for each chromosome. Additionally, study of the gene organization and phylogeny of the respective origins of replication confirmed the shared history. Conclusions Thus, while elements within the chromosomes may have experienced significant genetic mobility, the backbones share a common history. This allows conclusions based on multilocus sequence analysis (MLSA) for one chromosome to be applied equally to both chromosomes.
MIT Department
Broad Institute of MIT and Harvard
Massachusetts Institute of Technology. Department of Civil and Environmental Engineering
Terms of Use
Creative Commons Attribution
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1186/1471-2180-10-137
