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Self-referenced quantitative phase microscopy

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Author(s)
Hillman, Timothy Robert
•
Lue, Niyom
•
Sung, Yongjin
•
Dasari, Ramachandra Rao
•
So, Peter T. C.
•
Yaqoob, Zahid
Date Issued
February 2012
Publisher
SPIE-Intl Soc Optical Eng
Citation
Hillman, Timothy R., Niyom Lue, Yongjin Sung, Ramachandra R. Dasari, Peter T. C. So, and Zahid Yaqoob. “Self-Referenced Quantitative Phase Microscopy.” Edited by Jose-Angel Conchello, Carol J. Cogswell, Tony Wilson, and Thomas G. Brown. Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XIX (February 9, 2012).
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Final published version
Abstract
Self-referenced quantitative phase microscopy (SrQPM) is reported, wherein quantitative phase imaging is achieved through the interference of the sample wave with a reflected version of itself. The off-axis interference between the two beams generates a spatially modulated hologram that is analyzed to quantify the sample's amplitude and phase profile. SrQPM requires approximately one-half of the object field of view to be empty and optically flat, which serves as a reference for the other half of the field of view containing the sample.
MIT Department
Lincoln Laboratory
Massachusetts Institute of Technology. Department of Biological Engineering
Massachusetts Institute of Technology. Department of Chemistry
Massachusetts Institute of Technology. Department of Mechanical Engineering
Massachusetts Institute of Technology. Spectroscopy Laboratory
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Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
Persistent DSpace Link
http://hdl.handle.net/1721.1/120341
DOI of Published Version
https://doi.org/10.1117/12.909701
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