Discovery of Novel Materials with Broad Resistance to Bacterial Attachment Using Combinatorial Polymer Microarrays
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Author(s)
Hook, Andrew L.
Chang, Chien-Yi
Yang, Jing
Atkinson, Steve
Davies, Martyn C.
Williams, Paul
Alexander, Morgan R.
Anderson, Daniel Griffith
Langer, Robert S
Date Issued
February 2013
Journal
Advanced Materials
Publisher
Wiley Blackwell
Citation
Hook, Andrew L., Chien-Yi Chang, Jing Yang, Steve Atkinson, Robert Langer, Daniel G. Anderson, Martyn C. Davies, Paul Williams, and Morgan R. Alexander. “Discovery of Novel Materials with Broad Resistance to Bacterial Attachment Using Combinatorial Polymer Microarrays.” Advanced Materials 25, no. 18 (May 14, 2013): 2542-2547. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
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Final published version
Abstract
A new class of bacteria-attachment-resistant materials is discovered using a multi-generation polymer microarray methodology that reduces bacterial attachment by up to 99.3% compared with a leading commercially available silver hydrogel anti-bacterial material. The coverage of three bacterial species, Pseudomonas aeruginosa, Staphylococcus aureus, and uropathogenic Escherichia coli is assessed.
MIT Department
Harvard University--MIT Division of Health Sciences and Technology
Massachusetts Institute of Technology. Department of Chemical Engineering
Koch Institute for Integrative Cancer Research at MIT
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DOI of Published Version
https://doi.org/10.1002/adma.201204936
