A size‐adaptive 32‐channel array coil for awake infant neuroimaging at 3 Tesla MRI
Name
mrm.28791.pdf
Description
Published version
Size
1.58 MB
Format
Adobe PDF
Checksum (MD5)
4c02b92c16dc39e0f28f52451cb74c82
Author(s)
Ghotra, Anpreet
Kosakowski, Heather L
Takahashi, Atsushi
Etzel, Robin
May, Markus W
Scholz, Alina
Jansen, Andreas
Wald, Lawrence L
Kanwisher, Nancy
Saxe, Rebecca
Date Issued
2021
Journal
Magnetic Resonance in Medicine
Publisher
Wiley
Citation
Ghotra, Anpreet, Kosakowski, Heather L, Takahashi, Atsushi, Etzel, Robin, May, Markus W et al. 2021. "A size‐adaptive 32‐channel array coil for awake infant neuroimaging at 3 Tesla MRI." Magnetic Resonance in Medicine, 86 (3).
Version
Final published version
Abstract
PURPOSE: Functional magnetic resonance imaging (fMRI) during infancy poses challenges due to practical, methodological, and analytical considerations. The aim of this study was to implement a hardware-related approach to increase subject compliance for fMRI involving awake infants. To accomplish this, we designed, constructed, and evaluated an adaptive 32-channel array coil. METHODS: To allow imaging with a close-fitting head array coil for infants aged 1-18 months, an adjustable head coil concept was developed. The coil setup facilitates a half-seated scanning position to improve the infant's overall scan compliance. Earmuff compartments are integrated directly into the coil housing to enable the usage of sound protection without losing a snug fit of the coil around the infant's head. The constructed array coil was evaluated from phantom data using bench-level metrics, signal-to-noise ratio (SNR) performances, and accelerated imaging capabilities for both in-plane and simultaneous multislice (SMS) reconstruction methodologies. Furthermore, preliminary fMRI data were acquired to evaluate the in vivo coil performance. RESULTS: Phantom data showed a 2.7-fold SNR increase on average when compared with a commercially available 32-channel head coil. At the center and periphery regions of the infant head phantom, the SNR gains were measured to be 1.25-fold and 3-fold, respectively. The infant coil further showed favorable encoding capabilities for undersampled k-space reconstruction methods and SMS techniques. CONCLUSIONS: An infant-friendly head coil array was developed to improve sensitivity, spatial resolution, accelerated encoding, motion insensitivity, and subject tolerance in pediatric MRI. The adaptive 32-channel array coil is well-suited for fMRI acquisitions in awake infants.
MIT Department
Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Terms of Use
Creative Commons Attribution NonCommercial License 4.0
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DOI of Published Version
https://doi.org/10.1002/MRM.28791
