Manipulating the duration of picoinjection controls the injected volume of individual droplets
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044102_1_5.0206830.pdf
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2.16 MB
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6f73476ad27cb901baf98db573edc9e9
Author(s) •
Thakur, R.
Weitz, D.
Date Issued
July 2, 2024
Journal
Biomicrofluidics
Publisher
AIP Publishing
Citation
R. Thakur, D. Weitz; Manipulating the duration of picoinjection controls the injected volume of individual droplets. Biomicrofluidics 1 July 2024; 18 (4): 044102.
Version
Final published version
Abstract
The ability to add reagents into droplets is required in many microfluidic workflows. Picoinjection can address this need; however, it is unable to control the injection volume for each individual droplet. Here, we present an improved picoinjection method that can inject controlled volumes into individual droplets. We achieve this by adjusting the injection duration for each picoinjection event. This improved picoinjection method can be used to create complex microfluidic workflows that are able to control the biochemical composition of individual droplets.
MIT Department
Harvard University--MIT Division of Health Sciences and Technology
Terms of Use
Creative Commons Attribution
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1063/5.0206830