An Implantable MEMS Drug Delivery Device for Rapid Delivery in Ambulatory Emergency Care
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Elman_Implantable MEMS.pdf
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Author(s)
Elman, Noel
Ho Duc, Hong Linh
Cima, Michael J.
Date Issued
January 2009
Journal
Biomedical Microdevices
Publisher
Springer Netherlands
Citation
N. Elman, H. Ho Duc, and M. Cima, “An implantable MEMS drug delivery device for rapid delivery in ambulatory emergency care,” Biomedical Microdevices, vol. 11, Jun. 2009, pp. 625-631.
Version
Author's final manuscript
Abstract
We introduce the first implantable drug delivery system based on MEMS (Micro-Electro-Mechanical-Systems) technology specifically designed as a platform for treatment in ambulatory emergency care. The device is named IRD[superscript 3] (implantable rapid drug delivery device) and allows rapid delivery of drugs. Vasopressin was used as a model drug for in vitro tests as it is a commonly used drug for cardiac resuscitation. Experimental results reveal that the IRD3 provides an effective method for rapid delivery without significant drug degradation. Several medical uses and delivery modalities for IRD3 are proposed.
MIT Department
MIT Materials Research Laboratory
Massachusetts Institute of Technology. Department of Materials Science and Engineering
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Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
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DOI of Published Version
https://doi.org/10.1007/s10544-008-9272-6
