UniPROBE, update 2011: expanded content and search tools in the online database of protein-binding microarray data on protein–DNA interactions
Name
Robasky-2010-UniPROBE, update 2011.pdf
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6.77 MB
Format
Adobe PDF
Checksum (MD5)
fe6737502f0020d3732a505eecb1f5f5
Author(s)
Bulyk, Martha L.
Robasky, Kimberly
Date Issued
October 2010
Journal
Nucleic Acids Research
Publisher
Oxford University Press (OUP)
Citation
Robasky, K., and M. L. Bulyk. “UniPROBE, Update 2011: Expanded Content and Search Tools in the Online Database of Protein-binding Microarray Data on protein-DNA Interactions.” Nucleic Acids Research 39.Database (2010): D124–D128. Web. 1 June 2012.
Version
Final published version
Abstract
The Universal PBM Resource for Oligonucleotide-Binding Evaluation (UniPROBE) database is a centralized repository of information on the DNA-binding preferences of proteins as determined by universal protein-binding microarray (PBM) technology. Each entry for a protein (or protein complex) in UniPROBE provides the quantitative preferences for all possible nucleotide sequence variants (‘words’) of length k (‘k-mers’), as well as position weight matrix (PWM) and graphical sequence logo representations of the k-mer data. In this update, we describe >130% expansion of the database content, incorporation of a protein BLAST (blastp) tool for finding protein sequence matches in UniPROBE, the introduction of UniPROBE accession numbers and additional database enhancements. The UniPROBE database is available at http://uniprobe.org.
MIT Department
Harvard University--MIT Division of Health Sciences and Technology
Terms of Use
Creative Commons Attribution Non-Commercial
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DOI of Published Version
https://doi.org/10.1093/nar/gkq992
