Brain function and clinical characterization in the Boston adolescent neuroimaging of depression and anxiety study
Name
1-s2.0-S2213158220300772-main.pdf
Description
Published version
Size
3.82 MB
Format
Adobe PDF
Checksum (MD5)
ca4c4d4620859f3e8f66625ee081d44b
Author(s)
Date Issued
2020
Journal
NeuroImage: Clinical
Publisher
Elsevier BV
Version
Final published version
Abstract
© 2020 We present a Human Connectome Project study tailored toward adolescent anxiety and depression. This study is one of the first studies of the Connectomes Related to Human Diseases initiative and is collecting structural, functional, and diffusion-weighted brain imaging data from up to 225 adolescents (ages 14–17 years), 150 of whom are expected to have a current diagnosis of an anxiety and/or depressive disorder. Comprehensive clinical and neuropsychological evaluations and longitudinal clinical data are also being collected. This article provides an overview of task functional magnetic resonance imaging (fMRI) protocols and preliminary findings (N = 140), as well as clinical and neuropsychological characterization of adolescents. Data collection is ongoing for an additional 85 adolescents, most of whom are expected to have a diagnosis of an anxiety and/or depressive disorder. Data from the first 140 adolescents are projected for public release through the National Institutes of Health Data Archive (NDA) with the timing of this manuscript. All other data will be made publicly-available through the NDA at regularly scheduled intervals. This article is intended to serve as an introduction to this project as well as a reference for those seeking to clinical, neurocognitive, and task fMRI data from this public resource.
MIT Department
McGovern Institute for Brain Research at MIT
Harvard University--MIT Division of Health Sciences and Technology
Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Martinos Imaging Center (McGovern Institute for Brain Research at MIT)
Terms of Use
Creative Commons Attribution-NonCommercial-NoDerivs License
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1016/J.NICL.2020.102240
