Prefrontal cortex as a key node in arousal circuitry
Name
1-s2.0-S0166223622001448-main.pdf
Description
Published version
Size
1.29 MB
Format
Adobe PDF
Checksum (MD5)
7ecc5281948222905b59769a5d474dea
Author(s)
Mashour, George A
Pal, Dinesh
Brown, Emery Neal
Date Issued
2022
Journal
Trends in Neurosciences
Publisher
Elsevier BV
Citation
Mashour, George A, Pal, Dinesh and Brown, Emery N. 2022. "Prefrontal cortex as a key node in arousal circuitry." Trends in Neurosciences, 45 (10).
Version
Final published version
Abstract
The role of the prefrontal cortex (PFC) in the mechanism of consciousness is a matter of active debate. Most theoretical and empirical investigations have focused on whether the PFC is critical for the content of consciousness (i.e., the qualitative aspects of conscious experience). However, there is emerging evidence that, in addition to its well-established roles in cognition, the PFC is a key regulator of the level of consciousness (i.e., the global state of arousal). In this opinion article we review recent data supporting the hypothesis that the medial PFC is a critical node in arousal-promoting networks.
MIT Department
Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Terms of Use
Creative Commons Attribution-NonCommercial-NoDerivs License
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1016/J.TINS.2022.07.002
