Lignocellulose-based analytical devices: bamboo as an analytical platform for chemical detection
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Kuan-2015-Lignocellulose-based.pdf
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1.06 MB
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Author(s)
Kuan, Chen-Meng
York, Roger L.
Cheng, Chao-Min
Date Issued
December 2015
Journal
Scientific Reports
Publisher
Nature Publishing Group
Citation
Kuan, Chen-Meng, Roger L. York, and Chao-Min Cheng. “Lignocellulose-Based Analytical Devices: Bamboo as an Analytical Platform for Chemical Detection.” Scientific Reports 5 (December 21, 2015): 18570.
Version
Final published version
Abstract
This article describes the development of lignocellulose-based analytical devices (LADs) for rapid bioanalysis in low-resource settings. LADs are constructed using either a single lignocellulose or a hybrid design consisting of multiple types of lignocellulose. LADs are simple, low-cost, easy to use, provide rapid response, and do not require external instrumentation during operation. Here, we demonstrate the implementation of LADs for food and water safety (i.e., nitrite assay in hot-pot soup, bacterial detection in water, and resazurin assay in milk) and urinalysis (i.e., nitrite, urobilinogen, and pH assays in human urine). Notably, we created a unique approach using simple chemicals to achieve sensitivity similar to that of commercially available immunochromatographic strips that is low-cost, and provides on-site, rapid detection, for instance, of Eschericia coli (E. coli) in water.
MIT Department
Koch Institute for Integrative Cancer Research at MIT
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Creative Commons Attribution
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DOI of Published Version
https://doi.org/10.1038/srep18570
