Physical and mechanical properties of PLA, and their functions in widespread applications — A comprehensive review
Name
Anderson_Physical and mechanical properties.pdf
Size
3.03 MB
Format
Adobe PDF
Checksum (MD5)
67c8d68091466890805e776322f505a5
Author(s)
Farah, Shady
Anderson, Daniel Griffith
Langer, Robert S
Date Issued
June 2016
Journal
Advanced Drug Delivery Reviews
Publisher
Elsevier BV
Citation
Farah, Shady, et al. “Physical and Mechanical Properties of PLA, and Their Functions in Widespread Applications — A Comprehensive Review.” Advanced Drug Delivery Reviews, vol. 107, Dec. 2016, pp. 367–92.
Version
Author's final manuscript
Abstract
Poly(lactic acid) (PLA), so far, is the most extensively researched and utilized biodegradable aliphatic polyester in human history. Due to its merits, PLA is a leading biomaterial for numerous applications in medicine as well as in industry replacing conventional petrochemical-based polymers. The main purpose of this review is to elaborate the mechanical and physical properties that affect its stability, processability, degradation, PLA-other polymers immiscibility, aging and recyclability, and therefore its potential suitability to fulfill specific application requirements. This review also summarizes variations in these properties during PLA processing (i.e. thermal degradation and recyclability), biodegradation, packaging and sterilization, and aging (i.e. weathering and hygrothermal). In addition, we discuss up-to-date strategies for PLA properties improvements including components and plasticizer blending, nucleation agent addition, and PLA modifications and nanoformulations. Incorporating better understanding of the role of these properties with available improvement strategies is the key for successful utilization of PLA and its copolymers/composites/blends to maximize their fit with worldwide application needs. Keywords: Physical and mechanical properties; PLA; Biodegradable polymers; Polymer processing; Applications
MIT Department
Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Harvard University--MIT Division of Health Sciences and Technology
Massachusetts Institute of Technology. Department of Chemical Engineering
Koch Institute for Integrative Cancer Research at MIT
Terms of Use
Creative Commons Attribution-NonCommercial-NoDerivs License
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1016/J.ADDR.2016.06.012
