Lithiation and electrophilic substitution of dimethyl triazones
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Movassaghi_Lithiation and electrophilic.pdf
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371.43 KB
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Author(s)
Han, Sunkyu
Siegel, Dustin S.
Movassaghi, Mohammad
Date Issued
May 2012
Journal
Tetrahedron Letters
Publisher
Elsevier
Citation
Han, Sunkyu, Dustin S. Siegel, and Mohammad Movassaghi. “Lithiation and Electrophilic Substitution of Dimethyl Triazones.” Tetrahedron Letters 53, no. 29 (July 2012): 3722–3726.
Version
Author's final manuscript
Abstract
The lithiation and electrophilic substitution of dimethyl triazones is described. Directed lithiation or tin–lithium exchange of dimethyl triazones afforded the corresponding dipole stabilized nucleophiles that were trapped with various electrophiles. Keto-triazone derivatives accessed by acylation of such nucleophiles were readily converted into the corresponding imidazolone heterocycles.
MIT Department
Massachusetts Institute of Technology. Department of Chemistry
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Creative Commons Attribution-Noncommercial-NoDerivatives
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DOI of Published Version
https://doi.org/10.1016/j.tetlet.2012.04.121
