Thermally Switchable Polymers Achieve Controlled Escherichia coli Detachment
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Anderson_Thermally switchable.pdf
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Author(s) • • • • • • •
Hook, Andrew L.
Chang, Chien-Yi
Scurr, David J.
Williams, Paul
Davies, Martyn C.
Alexander, Morgan R.
Anderson, Daniel Griffith
Langer, Robert S
Date Issued
February 2014
Journal
Advanced Healthcare Materials
Publisher
Wiley Blackwell
Citation
Hook, Andrew L., Chien-Yi Chang, David J. Scurr, Robert Langer, Daniel G. Anderson, Paul Williams, Martyn C. Davies, and Morgan R. Alexander. “ Thermally Switchable Polymers Achieve Controlled Escherichia Coli Detachment .” Adv. Healthcare Mater. 3, no. 7 (February 4, 2014): 1020–1025.
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Author's final manuscript
Abstract
The thermally triggered release of up to 96% of attached uropathogenic E. coli is achieved on two polymers with opposite changes in surface wettability upon reduction in temperature. This demonstrates that the bacterial attachment to a surface cannot be explained in terms of water contact angle alone; rather, the surface composition of the polymer plays the key role.
MIT Department
Harvard University--MIT Division of Health Sciences and Technology
Massachusetts Institute of Technology. Department of Chemical Engineering
Koch Institute for Integrative Cancer Research at MIT
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DOI of Published Version
https://doi.org/10.1002/adhm.201300518