A stochastic tractography system and applications
Name
219720649-MIT.pdf
Description
Full printable version
Size
8.45 MB
Format
Adobe PDF
Checksum (MD5)
bf705556c6936d1e99e7e1e61f0779bb
Author(s)
Ngo, Tri M. (Tri Minh)
Advisor(s)
Polina Golland and Carl-Fredrik Westin.
Date Issued
2007
Publisher
Massachusetts Institute of Technology
Abstract
Neuroscientists hypothesize that the pathologies of some neurological diseases are associated with neuroanatomical abnormalities. Diffusion Tensor Imaging (DTI) and stochastic tractography allow us to investigate white matter architecture non-invasively through measurements of water self diffusion throughout the brain. Many comparative studies of white matter architecture utilize spatially localized comparisons of diffusion characteristics. White matter tractography enables studies of fiber bundle characteristics. Stochastic tractography facilitates these investigations by providing a measure of confidence regarding the inferred fiber bundles. This thesis presents an implementation of an easy to use, open-source stochastic tractography system that will enable novel studies of fiber tract abnormalities. We demonstrate an application of the system on real DTI images and discuss possible studies of frontal lobe fiber differences in Schizophrenia.
Description
Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2007.
Includes bibliographical references (p. 75-77).
Subjects
Electrical Engineering and Computer Science.
MIT Department
Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
Terms of Use
M.I.T. theses are protected by
copyright. They may be viewed from this source for any purpose, but
reproduction or distribution in any format is prohibited without written
permission. See provided URL for inquiries about permission.
copyright. They may be viewed from this source for any purpose, but
reproduction or distribution in any format is prohibited without written
permission. See provided URL for inquiries about permission.
Persistent DSpace Link
