Fluorescent Nanorods and Nanospheres for Real-Time In Vivo Probing of Nanoparticle Shape-Dependent Tumor Penetration
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Bawendi_Fluorescent nanorods.pdf
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1.42 MB
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Author(s)
Chauhan, Vikash P.
Popovic, Zoran
Chen, Ou
Cui, Jian
Fukumura, Dai
Bawendi, Moungi G.
Jain, Rakesh K.
Date Issued
October 2011
Journal
Angewandte Chemie International Edition
Publisher
Wiley Blackwell (John Wiley & Sons)
Citation
Chauhan, Vikash P. et al. “Fluorescent Nanorods and Nanospheres for Real-Time In Vivo Probing of Nanoparticle Shape-Dependent Tumor Penetration.” Angewandte Chemie International Edition 50.48 (2011): 11417–11420.
Version
Author's final manuscript
Abstract
Shape dependent: Fluorescent quantum-dot-based nanospheres and nanorods with identical hydrodynamic size and surface properties but different aspect ratios were developed for real-time in vivo tumor imaging. The nanorods exhibited superior transport and distribution into mammary tumors in vivo versus nanospheres of similar plasma half-life.
MIT Department
Massachusetts Institute of Technology. Department of Chemistry
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Creative Commons Attribution-Noncommercial-Share Alike 3.0
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DOI of Published Version
https://doi.org/10.1002/anie.201104449
