Self-Aligned Acoustofluidic Particle Focusing and Patterning in Microfluidic Channels from Channel-Based Acoustic Waveguides
Name
PhysRevLett.120.074502.pdf
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4.67 MB
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Author(s)
O’Rorke, Richard
Devendran, Citsabehsan
Ma, Zhichao
Neild, Adrian
Ai, Ye
Collins, David
Han, Jongyoon
Date Issued
February 2018
Journal
Physical Review Letters
Publisher
American Physical Society
Citation
Collins, David J. et al. "Self-Aligned Acoustofluidic Particle Focusing and Patterning in Microfluidic Channels from Channel-Based Acoustic Waveguides." Physical Review Letters 120, 7 (February 2018): 074502 © 2018 American Physical Society
Version
Final published version
Abstract
Acoustic fields have been widely used for manipulation of particles and cells within microfluidic systems. In this Letter, we explore a novel acoustofluidic phenomenon for particle patterning and focusing, where a periodic acoustic pressure field is produced parallel to internal channel boundaries with the imposition of either a traveling or standing surface acoustic wave (SAW). This effect results from the propagation and intersection of edge waves from the channel walls according to the Huygens-Fresnel principle and classical wave fronts from the substrate-fluid interface. We demonstrate versatile control over this effect to produce both one- and two-dimensional acoustic patterning from one-dimensional SAW fields and its utility for continuous particle focusing. Uniquely, this channel-guided acoustic focusing permits the generation of robust acoustic fields without channel resonance conditions and particle focusing positions that are difficult or impossible to produce otherwise.
MIT Department
Massachusetts Institute of Technology. Department of Biological Engineering
Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
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DOI of Published Version
https://doi.org/10.1103/PhysRevLett.120.074502
