Transcriptional activation of macropinocytosis by the Hippo pathway following nutrient limitation
Name
Genes Dev.-2020-Sivanand-1253-5.pdf
Description
Published version
Size
1.21 MB
Format
Unknown
Checksum (MD5)
f71d1bc5468e275864bc38276361b6f4
Author(s)
Sivanand, Sharanya
Vander Heiden, Matthew G.
Date Issued
2020
Journal
Genes and Development
Publisher
Cold Spring Harbor Laboratory
Version
Final published version
Abstract
Cancer cells must adapt metabolism to thrive despite nutrient limitations in the tumor microenvironment. In this issue of Genes & Development, King and colleagues (pp. 1345-1358) report a role for transcriptional regulators of the Hippo pathway to facilitate protein scavenging and support proliferation under some nutrient-deprived conditions.
MIT Department
Koch Institute for Integrative Cancer Research at MIT
Terms of Use
Creative Commons Attribution NonCommercial License 4.0
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1101/GAD.343632.120
