Open source model for generating RR intervals in atrial fibrillation and beyond
Name
1475-925X-6-9.pdf
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397.64 KB
Format
Adobe PDF
Checksum (MD5)
97e1434b4b6e50a2460b7c14236aaaa9
Author(s)
Lian, Jie
Clifford, Gari D.
Muessig, Dirk
Lang, Volker
Date Issued
March 2007
Journal
BioMedical Engineering Online
Publisher
BioMed Central Ltd
Citation
BioMedical Engineering OnLine. 2007 Mar 02;6(1):9
Version
Final published version
Abstract
Abstract Background Realistic modeling of cardiac inter-beat (RR) intervals is highly desirable for basic research in cardiac electrophysiology, clinical management of heart diseases, and developing signal processing tools for ECG analysis. Methods We present an open source computer model that is capable to generate realistic time series of RR intervals in both physiologic and pathologic conditions. Detailed model structure and the software implementation are described. Results Examples are provided on how to use this model to generate RR intervals in atrial fibrillation with ventricular pacing, normal sinus rhythm with heart rate variability, and typical atrial flutter with atrioventricular block. The extensibility of the model is also discussed. Conclusion The present computer model provides a unified platform wherein various types of ventricular rhythm can be simulated. The availability of this open source model promises to support and stimulate future studies.
MIT Department
Harvard University--MIT Division of Health Sciences and Technology
Terms of Use
Creative Commons Attribution
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1186/1475-925X-6-9
