Amplicon residues in research laboratories masquerade as COVID-19 in surveillance tests
Name
1-s2.0-S2667237521000059-main.pdf
Size
417.6 KB
Format
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Checksum (MD5)
032daceac778d1e1933a202f4ccbddd8
Author(s)
Davidi, Dan
Fitzgerald, Susan
Glaspell, Hannah L.
Jalbert, Samantha
Klapperich, Catherine M.
Landaverde, Lena
Maheras, Stylianos
Mattoon, Stephanie E.
Britto, Vanessa M.
Nguyen, Giang T.
Date Issued
April 2021
Journal
Cell Reports Methods
Publisher
Elsevier BV
Citation
Davidi, Dan et al. "Amplicon residues in research laboratories masquerade as COVID-19 in surveillance tests." Cell Reports Methods 1,1 (May 2021): 100005.
Version
Final published version
Abstract
Asymptomatic surveillance testing together with COVID-19-related research can lead to positive SARS-CoV-2 tests resulting not from true infections, but non-infectious, non-hazardous by-products of research (amplicons). Amplicons can be widespread and persistent in lab environments and can be difficult to distinguish for true infections. We discuss prevention and mitigation strategies.
MIT Department
MIT Medical
Terms of Use
Creative Commons Attribution-NonCommercial-NoDerivs License
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1016/j.crmeth.2021.100005
